1st Endurance - OPTYGEN

800-969-6199

See also: 1st Endurance Ultragen
At Victory Nutrition we did our usual homework. We reviewed the ingredients in Optygen using the Natural Medicines Comprehensive Database, an independent consensus of current scientific information on herbal medicines and dietary supplements. It apprears this may be one the most promising nutracueticals designed specifically for endurance athletes. Furthermore, certain ingredients in Optygen may have health benefits beyond those touted by First Endurance.

Optygen is unlike any other endurance product available. Optygen is a legal, safe and stimulant-free formula designed specifically to optimize performance for endurance athletes. This revolutionary formula is based on human clinical trials and the latest scientific research on increasing endurance.
The adaptogens in Optygen have been studied extensively for their ability to:

Increase VO2Max

Increase the body's ability to adapt to high levels of physical stress

Increase anaerobic threshold

Reduce lactic acid

Supplementwatch.com (an independent research company) evaluated nine of the most popular endurance supplements and Optygen was RANKED THE #1 ENDURANCE SUPPLEMENT. In the research study, Supplementwatch.com stated: "Optygen is certainly poised to offer a decent shot at improved oxygen efficiency -and reduced lactate and increase performance as a result." Procycling magazine added Optygen in their "Wish list" category in the September 2002 issue and said: Optygen is a "legal, pure and effective pill." and Optygen is "worth considering if you're a competing athlete."

Optygen Ranked #1 Endurance Supplement Again in 2004

Optygen was ranked the #1 endurance supplement again by SupplemenWatch.comTM. The 2004 review evaluated Optygen, and ten other popular endurance supplements, based on claims, theory, science, safety and value. Each of the five categories is scored from 1-20, with 100 total points possible. At the conclusion of the 2004 review, Optygen received the top score of 92 out of 100. Last year, Optygen was also awarded the #1 ranking in 2003 with a score of 90. The difference this year is that First Endurance increased the Rhodiola extract in the 2004 formulation.

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FS-FEOPTYG - OPTYGEN - 90 capsules - $49.95
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Every bottle of Optygen comes with a Certificate of Analysis that lists all of the ingredients that are used in the formula. The Certificates of Analysis shows that there are no banned ingredients in Optygen. In addition, Optygen also has a 100% performance guarantee. Here's what's in the formula (ingredient list at page bottom):
ATPRO
Optygen's proprietary ATPro matrix of five key nutrients is designed to assure Adenosine Triphosphate (ATP) production. Calcium pyruvate, sodium phosphate, potassium phosphate, adenosine and d-ribose all play critical roles in glycolysis and the citric acid cycle. It is this complex set of chemical reactions which produce ATP aerobically. Clinical research has shown that endurance athletes diminish their ATP stores in exhaustive exercise which can lead to a reduction in aerobic metabolism and endurance. One's VO2max is directly proportional to their ability to produce ATP which is also known as the body's high energy state.
RHODIOLA ROSEA
Rhodiola is comprised of many different species and is generally found in the high mountain region of Siberia above 7,000 feet or on the Tibetan plateau above 12,000 feet. For many years, Russian athletes and scientists have touted the strong medicinal properties of this rare herb. The root of the plant sometimes referred to as golden root is used in the current medicinal applications. One of the adaptogenic applications of rhodiola that has received considerable research attention recently is for aiding adaptation to high altitudes, thus, as a preventive treatment for hypoxia or mountain sickness (Zhang Weiyun, 1997; Wang Liang, 1999; Qian Yancong, et al., 1999). There are six known polyphenol active compounds in Rhodiola. The two most active are salidrosides and rosavins. Many of the clinical studies on hypoxia and oxygen transfer characteristics isolate these two active compounds.

Mechanism of Action: Recent clinical research supports the energizing and anti-hypoxic effects claimed by Traditional Chinese Medicine and Russian researchers. In the 1986 study by Kuruov it was concluded that Rhodiola extended life significantly in states of hypoxia. Rhodiola exhibited this effect through a lowering of arterial pressure, reduced heart rate and lengthening the phases of cardiac contractions. (Kurukov 1986). Researcher Carl Germano concludes that Rhodiola has the ability to rapidly normalize lactic acid accumulation. A newly issued patent on Rhodiola proved that Rhodiola has the ability to increase blood oxygen, improve cardiac function and improve mitochondrial oxidative phosphorylation. (Xiu, 2002) Researchers believe the tissue differentiation or plasmodesmata within the compact callus aggregates (CCA) may provide capillaries for improving transport of oxygen and other nutrients. (Xu J, 1998).
CORDYCEPS SINESIS CS-4
Cordyceps Sinensis CS-4 Background: Cordyceps Sinensis is a highly valued medicinal mushroom in Traditional Chinese Medicine (TCM). Cordyceps has long been used to treat lung disease and fatigue. The Cordyceps mushroom grows primarily on the plateau of China and Tibet above 12,000 feet. Some researchers believe it is the mushroom's ability to survive at high altitude, which give it its blood oxygenating properties. The CS-4, is a fermentable strain of the mycelia (Paecilomyces hepiali C.) isolated from the natural Cordyceps Sinensis collected from the QuinHai. CS-4 is used to produce fermented mycelia product that contains the same pharmacologically active compounds as the natural Cordyceps Sinensis, specifically cordycepic acid. It is important to note, the clinical research on endurance, fatigue and VO2max has only been done with the CS-4 strain.

Mechanism of action: Recent clinical research supports the anti-fatigue claims of Cordyceps Sinensis in TCM. Cordyceps CS-4 research shows that it can increase endurance and energy through more efficient enzyme activity of Red Blood Cells while improving lung and kidney function. CS-4 mobilizes free fatty acids and beta-oxidation, thereby preserving glycogen usage during prolonged exercise. (Medicine & Science in Sports & Exercise, 2001) In both animal and human studies CS-4 has proved to support the enzyme superoxide dismutase (SOD). (J. Zhu, 1999). In a human study, Cordyceps has proved to improve lactate energy metabolism within the cell. (Burke, Edmund 1998)
CHROMIUM (AS CHELATE)
Chromium Chelavite: Chromium is an essential trace mineral that aids in glucose metabolism, regulation of insulin levels, and maintenance of healthy blood levels of cholesterol and other lipids. Chromium forms part of a compound in the body known as glucose tolerance factor (GTF), which is involved in regulating the actions of insulin in maintaining blood sugar levels and, possibly, in helping to control appetite. Food sources include brewer's yeast, whole grain cereals, broccoli, prunes, mushrooms and beer. The most widely available supplements are chromium salts such as chromium polynicotinate, chromium picolinate and chromium chelated - which help increase the absorption and availability compared to isolated chromium. *Chelavite, is a patented (US Patent #5,614,553) chelated form of Chromium with enhanced bioavailability and uptake.
INGREDIENTS:
Loading Phase: Take six (6) capsules every morning for (7) days.
Maintenance Phase: After loading phase, take three (3) capsules every morning.

Supplement Facts
Serving Size: 3 Capsules

Amount Per Serving %DV

Chromium (as Chelavite amino acid Chelate) 200mcg 167%

Cordyceps CS-4 (Cordyceps Sinensis) (mycelia biomass) minimum 7% cordycepic acid 1000mg *

ATPro^TM Matrix (Calcium Pyruvate, Sodium Phosphate, Potassium Phosphate, Ribose, Adenosine) 800mg *

Rhodiola Extract (Rhodiola Rosea)(root) minimum 2.5% salidrosidesminimum 3.0% rosavins 300mg *

Other Ingredients: no processing ingredients added

Chelavite is a registered trademark of Albion laboratories, Inc.
Covered by Albion international, Inc., U.S. Patent 5,614,553.

Potency, Purity & Quality Guaranteed: First Endurance uses only the finest ingredients and follows stringent quality control. Optygen is packaged in amber glass and red capsules in order to minimize degredation from UV light, oxygen and moisture, ensuring you receive the highest potency and purity.
Additional reading and studies supporting ingredients in Optygen

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any desease.
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